بسم الله الرحمن الرحيم
If when using an injection to insert (any medicine or) glucose (into the body), a lot of blood (i.e. that amount of blood which would have been able to flow on its own) comes back into the needle, even though it goes back into the body with the medicine, the wudhu will break.
If the amount of blood that came out into the needle was little (i.e. not enough to flow) then the wudhu will not break.
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للمفتي محمد أشرف الاشاعتي
Vol.1 Pg.107